Rolimus 10mg Tablet 10’S


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Manufacturer Cipla Ltd
Country of Origin INDIA
Composition EVEROLIMUS 10MG
Packing Size 10 Tablet(s)







What ROLIMUS 10MG is used for?

  • ROLIMUS 10MG reduces the blood supply to the tumour and slows down the growth and spread of cancer cells

It is used to treat adult patients with

  • Hormone receptor-positive advanced breast cancer in postmenopausal women and advanced kidney cancer (advanced renal cell carcinoma), where other treatments have not helped
  • Advanced tumours called neuroendocrine tumours that originate from the stomach, bowels, lung or pancreas. It is given if the tumours are inoperable and do not overproduce specific hormones or other related natural substances

 Warning & Precautions

Talk to Doctor

Talk to your doctor before you take this medicine, if you:

  • Are allergic to any of the ingredients of this medicine
  • Have liver problems
  • Have diabetes
  • Need to receive a vaccine
  • Have high cholesterol
  • Have had recent major surgery
  • Have previously had hepatitis B

Pregnancy & Breast Feeding

  • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine

Children & Adolescents

  • It is not to be used in children or adolescents age below 18 years

Driving & Using Machines

  • If you feel unusually tired (fatigue is a very common side effect), take special care when driving or using machines


Tell your doctor if you are taking,

  • Ketoconazole, itraconazole, voriconazole or fluconazole and other antifungals used to treat fungal infections
  • Clarithromycin, telithromycin or erythromycin, antibiotics used to treat bacterial infections
  • Ritonavir and other medicines used to treat HIV infection/AIDS
  • Verapamil or diltiazem, used to treat heart conditions or high blood pressure
  • Ciclosporin, a medicine used to stop the body from rejecting organ transplants
  • Imatinib, used to inhibit the growth of abnormal cells
  • Nefazodone, used to treat depression
  • Rifampicin, used to treat tuberculosis
  • Dexamethasone, a corticosteroid used to treat a wide variety of conditions including inflammatory or immune problems
  • Phenytoin, carbamazepine or phenobarbital and other anti-epileptics used to stop seizures or fits

 How to Use
  • Always take this medicine exactly as your doctor has told you
  • Swallow the tablet whole with a glass of water
  • Do not chew or crush this medicine
  • Rolimus 10mg should be taken without food
  • Do not start everolimus and consult your doctor if you have liver problems, diabetes, high blood cholesterol, had a recent surgery or have unhealed wound after surgery, have infection, previously had hepatitis, are pregnant or breast-feeding or have intolerance to some sugars.
  • Seek medical advice if you have increased thirst or increased frequency of urination, if you get any infection, suffer from shortness of breath, cough or fever, need to receive any vaccination after taking everolimus.
  • Everolimus may affect male or female fertility; consult your doctor if you are planning to have a child.
  • Do not drive or operate machinery while taking everolimus as it may cause fatigue.

If you take more ROLIMUS 10MG

  • If you have taken too much ROLIMUS 10MG, or if someone else accidentally takes your tablets, see a doctor or go to a hospital immediately

If you forget to take ROLIMUS 10MG

  • If you miss a dose, take your next dose as scheduled. Do not take a double dose to make up for the forgotten tablets

If you stop taking ROLIMUS 10MG

  • Do not stop taking this medicine unless your doctor tells you

 Side Effects

Like all medicines, this medicine can cause side effects, although not everybody gets them

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue or throat
  • Severe itching of the skin, with a red rash or raised bumps
  • Increased temperature, chills (signs of infection)
  • Fever, coughing, difficulty breathing, wheezing
  • Excessive thirst, high urine output, increased appetite with weight loss, tiredness (signs of diabetes)
  • Loss of appetite, nausea or diarrhoea, weight loss
  • Disturbed taste (dysgeusia)
  • Nose bleeds (epistaxis)
  • Feeling weak or tired
  • Pale skin, signs of low level of red blood cells (anaemia)
  • Swelling of arms, hands, feet, ankles or other part of the body (signs of oedema)
  • High level of lipids (fats) in the blood (hypercholesterolemia)
  • Spontaneous bleeding or bruising (signs of low level of platelets, also known as thrombocytopenia)
  • Trouble sleeping (insomnia)
  • Difficulty in swallowing (dysphagia)
  • Joint pain
  • Menstruation disorders such as irregular periods
  • Low level of potassium, phosphate and calcium in the blood
  • Hair loss
  • Coughing up blood (hemoptysis)
  • Chest pain
  • Abnormal wound healing
  • Hot flushes
  • Pink eye or red eye (conjunctivitis)

 More Information
  • Keep this medicine out of reach of children
  • Store at room temperature (15-25°C)
  • Do not use this medicine after the expiry date

Q. Is any monitoring required while taking Rolimus?
Regular monitoring is required while you are on Rolimus. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Rolimus. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
Q. What should I avoid while taking Rolimus?
You should avoid grapefruit or grapefruit juice while taking Rolimus. This is because taking them together may increase the levels of Rolimus in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Q. What is the most important information I need to know about Rolimus?
Rolimus can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Q. Is Rolimus a chemotherapy?
Rolimus is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Q. How is Rolimus administered?
Usually, Rolimus is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Rolimus should be swallowed whole with water and should not be crushed or chewed.
Q. How long can you take Rolimus?
There is no definite duration of treatment with Rolimus. Rolimus is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Q. How will I know that Rolimus is shrinking my brain tumor?
The effect of Rolimus in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Q. Is Rolimus cytotoxic?
Yes, Rolimus is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).


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